Senior Director: Cell Engager Portfolio Lead, ODDU
Company: Takeda Pharmaceutical
Location: Boston
Posted on: October 30, 2024
Job Description:
By clicking the "Apply" button, I understand that my employment
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with Takeda's and . I further attest that all information I submit
in my employment application is true to the best of my
knowledge.Job DescriptionAre you looking for a patient-focused,
innovation-driven company that will inspire you and empower you to
shine?At Takeda, we are transforming the pharmaceutical industry
through our R&D-driven market leadership and being a values-led
company. To do this, we empower our people to realize their
potential through life-changing work. Certified as a Global Top
Employer, we offer stimulating careers, encourage innovation, and
strive for excellence in everything we do. We foster an inclusive,
collaborative workplace, in which our global teams are united by an
unwavering commitment to deliver Better Health and a Brighter
Future to people around the world.Here, you will be a vital
contributor to our inspiring, bold mission.Takeda is proud in its
commitment to creating a diverse workforce and providing equal
employment opportunities to all employees and applicants for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, gender expression, parental status,
national origin, age, disability, citizenship status, genetic
information or characteristics, marital status, status as a Vietnam
era veteran, special disabled veteran, or other protected veteran
in accordance with applicable federal, state and local laws, and
any other characteristic protected by lawOBJECTIVES/PURPOSEThe
Oncology Drug Discovery Unit (ODDU) is looking for a Leader who
will serve as Senior Director, Cell Engager Portfolio Lead
reporting into the Solid and Heme Tumor Targeted Therapies Drug
Discovery Lead. The individual should have strong Drug Discovery
experience applying a disease-first strategy focused on
understanding and exploiting the underlying mechanisms of a disease
to develop lead assets while training a skilled scientific team. -
This strategic leader is able and willing to contribute to projects
moving from target identification and validation through early
clinical proof of concept.This candidate will have a deep
comprehension of biology (immuno-oncology biology, biologics,
translation), strong leadership skills, the ability to apply
innovative research biology approaches to provide scientific
insights, and the ability to think critically about long-term
strategy anticipating the future needs in the field of cell
engagers and beyond. The candidate will also serve on the
scientific leadership team of the ODDU and is responsible for peer
review of data package plans, agreement on innovation priorities,
generating clear data package expectations that enable the ability
to easily track progress and address potential issues. - The
candidate is expected to be influential across the entire drug
discovery spectrum in Research (beyond Oncology). - Using their
enterprise mindset, the candidate will in partnership with other
Research functions help to accelerate development of Takeda's
discovery portfolio and in partnership with other therapeutic areas
to accelerate development of Takeda's discovery
portfolio.ACCOUNTABILITIES
- This leader will be responsible for leading research for
selected innovative cell engager and targeted therapies at Takeda
and will work closely with Research and Development project teams,
Portfolio Leads, Discovery Leads and Lab Heads to develop the
strategies and to enable execution of robust, decision-enabling
preclinical and translation experiments.
- The leader is expected to develop, define, and effectively
communicate the vision and strategy of the Cell Engager team as it
relates to contributing to an industry-leading research portfolio
in collaboration with other Portfolio Leads across the DDU.
- Builds and mentors a team tailored to the vision and strategic
imperatives of the ODDU.
- The leader is a scientific driver for research strategy that
brings in external innovation to supplement internal pipeline
priorities in partnership with CEI (Center for External
Innovation)
- Oversee the work of Discovery Leads, Lab Head and team
providing feedback and detailed scientific guidance and taking
corrective action as needed.
- Develop, drive, and execute the Research plans for selected
cell engager programs to support pre-IND packages for the DDU
portfolio in partnership with Discovery Leads and Lab Head and
team.
- Represent ODDU within R&D and the TAU, as well as to
external stakeholders with respect to the cell engager programs
being supported.
- Drive and deliver the pre-clinical development of cell engager
programs and across the ODDU portfolio, leveraging resources as
needed on key ODDU initiatives and assets. -
- Serve as an experienced thought leader for Immuno-Oncology &
Translational Oncology within Takeda, guiding the research strategy
and ensuring its successful execution while supporting talent
development as a strong mentor and role model for cell engager
research.
- Develop and deliver on the design, execution, and analysis of
mechanism of action and proof-of concept studies, in close
partnership across ODDU, R&D, and the TAU, including
perspective across the continuum of discovery and development with
a global perspective.
- Support business critical decision making for pre-IND packages
within the cell engager pipeline, and the broader Takeda ODDU
portfolio.
- Leverage up-to-date knowledge of drug development and
competitive landscape at internal governance bodies as well as at
key interfaces with external partners, to guide decision
making.
- Drive biology focus with solid translation and clinical path in
partnership with Research and TAU (Therapeutic Area Unit)
partners.
- Provide direction for the identification of new targets aligned
with the iDAS (integrated disease area strategy) in collaboration
with the Oncology Development Therapeutic Area Unit and the
Oncology Business Unit.---
- Provide significant input into overall ODDU portfolio and
department strategy.
- Provide leadership and strategic support across Research,
and/or to external collaborators.
- Responsible for management of resourcing and budget planning
for the cell engager field.
- Ability to work in a highly matrixed environment and establish
robust connections between the biology and translational team,
engaging cross-functional teams to support projects.
- Work closely with in-house and external partners in developing
solid translational and research plans, in interpreting results,
and in determining next steps to maximize patient-centered value of
the portfolio.EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS: -
- PhD in Immunology or related field with 12+ years of industry
experience.
- 7 (Director)-9 (Senior Director) years of Industry experience
required, and 7 (Director)-9 (Senior Director) years of managerial
experience required.
- Excellent knowledge in biologics, immunology, oncology, and
drug discovery is required.
- Excellent oral and written communication skills, including
writing, reviewing and editing scientific documents and presenting
to a range of stakeholders.
- Ability to work and drive decision-making within a
multi-disciplinary, multi-regional, matrix teams with a global
perspective with cultural competency.
- Good fit with Takeda core values and leadership principles,
including the highest personal values and ethical standards.
- Takeda's high-engagement and ONE Research DEI culture is an
important factor in our success; we seek team members who will
contribute to and further strengthen that culture in all ways of
working.
- Right attitude (agile, curious, positive, open-minded, "can-do"
mindset), must be willing and able to be "hands on,"
results-oriented mindset.
- Effective leadership, people management, communication skills,
and a team builder management style are essential.
- Ability to take an enterprise mindset to enable the success of
Takeda.#LI-JT1Takeda Compensation and Benefits SummaryWe understand
compensation is an important factor as you consider the next step
in your career. We are committed to equitable pay for all
employees, and we strive to be more transparent with our pay
practices. -For Location:Boston, MAU.S. Base Salary
Range:$205,100.00 - $322,300.00The estimated salary range reflects
an anticipated range for this position. The actual base salary
offered may depend on a variety of factors, including the
qualifications of the individual applicant for the position, years
of relevant experience, specific and unique skills, level of
education attained, certifications or other professional licenses
held, and the location in which the applicant lives and/or from
which they will be performing the job.---The actual base salary
offered will be in accordance with state or local minimum wage
requirements for the job location. -U.S. based employees may be
eligible for short-term and/ or long-term incentives. U.S. based
employees may be eligible to participate in medical, dental, vision
insurance, a 401(k) plan and company match, short-term and
long-term disability coverage, basic life insurance, a tuition
reimbursement program, paid volunteer time off, company holidays,
and well-being benefits, among others. U.S. based employees are
also eligible to receive, per calendar year, up to 80 hours of sick
time, and new hires are eligible to accrue up to 120 hours of paid
vacation. -EEO StatementTakeda is proud in its commitment to
creating a diverse workforce and providing equal employment
opportunities to all employees and applicants for employment
without regard to race, color, religion, sex, sexual orientation,
gender identity, gender expression, parental status, national
origin, age, disability, citizenship status, genetic information or
characteristics, marital status, status as a Vietnam era veteran,
special disabled veteran, or other protected veteran in accordance
with applicable federal, state and local laws, and any other
characteristic protected by law.LocationsBoston, MAWorker
TypeEmployeeWorker Sub-TypeRegularTime TypeFull time
Keywords: Takeda Pharmaceutical, Brockton , Senior Director: Cell Engager Portfolio Lead, ODDU, Executive , Boston, Massachusetts
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