Senior Scientist, Image Analysis
Company: Disability Solutions
Location: Cambridge
Posted on: May 3, 2024
Job Description:
Working with UsChallenging. Meaningful. Life-changing. Those
aren't words that are usually associated with a job. But working at
Bristol Myers Squibb is anything but usual. Here, uniquely
interesting work happens every day, in every department. From
optimizing a production line to the latest breakthroughs in cell
therapy, this is work that transforms the lives of patients, and
the careers of those who do it. You'll get the chance to grow and
thrive through opportunities uncommon in scale and scope, alongside
high-achieving teams rich in diversity. Take your career farther
than you thought possible.Bristol Myers Squibb recognizes the
importance of balance and flexibility in our work environment. We
offer a wide variety of competitive benefits, services and programs
that provide our employees with the resources to pursue their
goals, both at work and in their personal lives. Read more:
careers.bms.com/working-with-us .When you join BMS, you are joining
a diverse, high-achieving team united by a common mission. The
Informatics and Predictive Sciences (IPS) mission is to Pioneer,
Partner and Predict to drive transformative insights for patient
benefit. IPS conducts applied computational research in areas that
include genomic, structural and molecular informatics,
computational and systems biology, patient selection and
translational biomarker research, and broader fields including
knowledge science, epidemiology and machine learning-across the
full lifecycle of drug discovery and development and across all
therapeutic areas at BMS. We do this in close partnership with
scientific and clinical experts in the field, both inside and
outside the company." We perform innovative science to empower key
data-driven decisions across a rich pipeline of next-generation
medicines. In doing so, our work transforms the lives of patients,
as well as our own lives and careers.Here, you'll get the chance to
grow and thrive through opportunities that are uncommon in scale
and scope. You'll pursue innovative ideas while advancing
professionally alongside some of the brightest minds in
biopharma.We are seeking a highly motivated scientist with
extensive research experience in image analysis and feature
extraction of H&E and/or immunohistochemistry (IHC) stains to
join our Computational Tissue Imaging Research team in the
Translational Bioinformatics group. This group of computational
scientists is responsible for advancing Bristol Myers Squibb's
industry-leading pipeline through the strategic application of
cutting-edge tissue-based image analysis and bioinformatics
approaches . The team collaborates with various internal
stakeholders , including pathologists, biologists, and other
bioinformaticians to understand mechanism of action ( MoA ) and
identify novel tissue-based biomarker . The team interacts with and
impacts all aspects of R&D at BMS, from early discovery through
late-stage development. The successful candidate must have
experience in utilizing off-the-shelf image analysis p latforms to
aid in the quantification of IHC staining expression, including
tissue histology classification s and cellular feature engineering
& quantification . The candidate should be able to perform
statistical analyses and data visualization using data analysis
packages such as R, Python, and/or MATLAB. Responsibilities
- Hands-on implementation/support of pathology whole slide image
analysis tools and technology .
- Work alongside image scientists in the digital pathology group
to manage, prepare and analyze pathology whole slide images to
support translational research across multiple disease /therapeutic
areas including oncology, immunology , and neuroscience .
- Manage project scope and deliverables with digital pathology
related external vendors and strategic collaborations with academic
institutions.
- Collaborate with biology and pathology colleagues to define
analysis plans and derive features for analysis .
- Perform bioinformatics analyses and data visualization,
including analytics associating image analysis features with
response and survival data, genetic features and other sample
attributes using cox regression models, hypothesis testing, ROC
analysis, and other statistical tools .
- Active participation in the testing of pathology image
management and analysis systems, tools, and technology .
- Prepare and present findings from image analysis projects to
other groups within BMS .
- Collaborate with other image scientists to propose, review ,
and finalize future image analysis algorithm development and
project work . Basic Qualifications:
- Bachelor's Degree in Biomedical Engineering, Bioinformatics,
Computer Science, or related discipline and 7+ years of academic /
industry experience
- or Master's Degree in Biomedical Engineering, Bioinformatics,
Computer Science, or related discipline and 5+ years of academic /
industry experience
- or PhD in Biomedical Engineering, Bioinformatics, Computer
Science, or related discipline and 2+ years of academic / industry
experiencePreferred Qualifications:
- Ph . D . in Biomedical Engineering, Bioinformatics, Computer
Science, or related discipline; or M.S. with 2 or more years of
related experience in a university pathology lab or pharmaceutical
or biotech company .
- Fluent in one or more digital pathology analysis software
packages; including HALO, Visiopharm , QuPath and/or other image
analysis platforms .
- Preference for p rior experience working within the
biotech/pharma industry, processing and analyzing digitized
pathology whole slide pathology images.
- Excellent programming skills in one or more analytics packages
such as R, Python and/or MATLAB.
- Knowledge of various digital imaging scanner and/or experience
imaging chromogen and fluorescent stains is desired.
- Prior experience in developing image analysis algorithms in
feature extraction of tumor, stroma, and various cell types through
stains and morphometric features.
- Prior experience with applying machine learning and/or deep
learning tools for medical imaging tasks is a plus .
- Strong problem-solving and collaboration skills, and rigorous
and creative thinking .
- Excellent written and oral communication skills, including an
ability to collaborate effectively with lab scientists and
pathologists .
- Ability to work both independently and collaboratively, and to
handle several concurrent, fast-paced projects.
- Track record of scientific leadership exemplified by first
author peer-reviewed publications , ideally related to pathology
image analysis . The starting compensation for this job is a range
from $109,000 - $150,700, plus incentive cash and stock
opportunities (based on eligibility). The starting pay rate takes
into account characteristics of the job, such as required skills
and where the job is performed. Final, individual compensation will
be decided based on demonstrated experience. Eligibility for
specific benefits listed on our careers site may vary based on the
job and location. For more on benefits, please visit our BMS Career
Site. Benefit offerings are subject to the terms and conditions of
the applicable plans then in effect and may include the following:
Medical, pharmacy, dental and vision care. Wellbeing support such
as the BMS Living Life Better program and employee assistance
programs (EAP). Financial well-being resources and a 401(K).
Financial protection benefits such as short- and long-term
disability, life insurance, supplemental health insurance, business
travel protection and survivor support. Work-life programs include
paid national holidays and optional holidays, Global Shutdown days
between Christmas and New Year's holiday, up to 120 hours of paid
vacation, up to two (2) paid days to volunteer, sick time off, and
summer hours flexibility. Parental, caregiver, bereavement, and
military leave. Family care services such as adoption and surrogacy
reimbursement, fertility/infertility benefits, support for
traveling mothers, and child, elder and pet care resources. Other
perks like tuition reimbursement and a recognition program.If you
come across a role that intrigues you but doesn't perfectly line up
with your resume, we encourage you to apply anyway. You could be
one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing CareersWith a single
vision as inspiring as Transforming patients' lives through
science--- , every BMS employee plays an integral role in work that
goes far beyond ordinary. Each of us is empowered to apply our
individual talents and unique perspectives in an inclusive culture,
promoting diversity in clinical trials, while our shared values of
passion, innovation, urgency, accountability, inclusion and
integrity bring out the highest potential of each of our
colleagues.On-site Protocol BMS has a diverse occupancy structure
that determines where an employee is required to conduct their
work. This structure includes site-essential, site-by-design,
field-based and remote-by-design jobs. The occupancy type that you
are assigned is determined by the nature and responsibilities of
your role: Site-essential roles require 100% of shifts onsite at
your assigned facility. Site-by-design roles may be eligible for a
hybrid work model with at least 50% onsite at your assigned
facility. For these roles, onsite presence is considered an
essential job function and is critical to collaboration,
innovation, productivity, and a positive Company culture. For
field-based and remote-by-design roles the ability to physically
travel to visit customers, patients or business partners and to
attend meetings on behalf of BMS as directed is an essential job
function. BMS is dedicated to ensuring that people with
disabilities can excel through a transparent recruitment process,
reasonable workplace accommodations/adjustments and ongoing support
in their roles. Applicants can request a reasonable workplace
accommodation/adjustment prior to accepting a job offer. If you
require reasonable accommodations/adjustments in completing this
application, or in any part of the recruitment process, direct your
inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/
eeo -accessibility to access our complete Equal Employment
Opportunity statement. BMS cares about your well-being and the
well-being of our staff, customers, patients, and communities. As a
result, the Company strongly recommends that all employees be fully
vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your
area.Any data processed in connection with role applications will
be treated in accordance with applicable data privacy policies and
regulations.
Keywords: Disability Solutions, Brockton , Senior Scientist, Image Analysis, Other , Cambridge, Massachusetts
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